SINULEX® FORTE SYRUP may assist in the symptomatic relief of the symptoms of a common cold, including coughs, nasal congestion and sinusitis. Sinulex Forte Syrup is suitable for children over 2 years of age and adults.

Sinulex® Forte Syrup

  • Antimicrobial
  • May prevent bacterial infections
  • May shorten the duration of infection
  • Loosens mucous
  • Expectorant
  • Anti-inflammatory
  • Antiviral

Ingredients

Primula Veris flower 28 g
Field Sorrel herb 28 g
Elder Flower 28 g
Verbena herb 28 g
Yellow Gentian root 9 g

Free from lactose, GMO, gluten, sugar, tartrazine and soya. Does not contain pseudoephedrine or any stimulants such as caffeine.


Primula Veris flower (also known as cowslip) has a long history of medicinal use and is known for its anti-inflammatory1, diuretic, antimicrobial, antifungal and antioxidant activity.2-4

The plant contains saponins, which have an expectorant effect.5 Primula Veris flower is a clinically and pharmacologically well-documented modern plant-based medicine for the relief of bronchitis, catarrhs of the respiratory tract and chronic coughs (especially those associated with chronic bronchitis and catarrhal congestion), as it is a well-know antispasmodic.

Field Sorrel herb (also known as sheep sorrel and botanically called Rumex acetosella) is known in the plant medicine world for its anti-inflammatory6 action. Sorrel is used traditionally to reduce swelling of the nasal passages and respiratory tract, and for treating bacterial infections. The tannins in sorrel have a drying effect and reduces mucous production.

Elder Flower (botanically called Sambucus nigra). An elder flower infusion is known to be very effective in the treatment of chest complaints and acts as an expectorant7. It relieves asthmatic symptoms and spurious croup8 in children. Traditionally elder flower has been used in the management of swollen sinuses, coughs and upper respiratory cold infections, bronchitis, hoarseness, shortness of breath and general flu symptoms.9 European folk medicine has employed the elderflower as an antiviral, and traditional Chinese medicine documented a related species, Sambucus williamsii, as an anti-inflammatory.

Recent studies have indeed identified evidence of the Elder Flower’s efficacy as an antiviral. In 1995, researchers Zakay-Rones et al. conducted a placebo-controlled study using the extract during an outbreak of influenza B in a small community in Panama – the results were dramatic. Over 90% of the group treated with Elder extract, showed significant improvement of symptoms within 2 days, compared with 16.7% of controls. Since that initial study, several laboratory studies have supported the plants’ anti-influenza efficacy against both A and B human influenza viruses.

In a study of Norwegian patients with flu-like symptoms, those given Elder Flower’s extract recovered four days sooner than those given a placebo.10

Verbena herb 

The Verbena herb has mucolytic and anti-inflammatory action11. Traditionally, Lemon verbena has been used to treat sore throats and respiratory tract diseases such as asthma and whooping cough.  The leaves and flowering stems are antibacterial and antispasmodic.12-18 Further investigation has shown anti-rhinosinusitis activity.

Yellow Gentian root 

The Yellow Gentian plant, which has not flowered, stores the richest medicinal properties in its roots. Also known as ‘bitter root’, the root of Yellow Gentian has an anti-inflammatory19 action and has been widely used as an excellent tonic.  It is also antibacterial20 and effective for treating infections such as sinusitis, cough, colds and other related symptoms. It provides the body the required antioxidants21 and nutrients to combat these issues.

Conclusion

The art of the combination of herbal preparations is a typical feature within phytotherapy and has been at the heart of herbal medicine for thousands of years and in all ancient cultures. A combined herbal preparation has the potential of becoming more than the sum of its parts; otherwise known as the synergistic effect.

The herbal extracts in Sinulex® forte Syrup were selected because of their anti-inflammatory action, their ability to protect the mucous membranes, and expel thick mucous.

Sinulex® Forte Syrup comes in 100 ml bottle.

Dosage

It is recommended to take this dosage for 7 to 14 consecutive days. Take in three daily doses, once in the morning, once midday and once in the evening, either undiluted or mixed with some water. Patents with gastrointestinal sensitivity to take Sinulex® Forte Syrup after meals. If the symptoms worsen or persist, please consult your healthcare provider.

Children aged 2 to 5 years: take 2,1 ml 3 times daily.

Children aged 6 to 11 years: take 3,5 ml 3 times daily.

Adults and adolescents above 12 years: take 7 ml 3 times daily.

Do not exceed the recommended or prescribed daily dosage. Shake well before use.

Side-effects or warnings

  • Avoid in cases of known hypersensitivity (allergies) to any of the mentioned ingredients.
  • Yellow Gentian root might lower blood pressure.
  • Safety during pregnancy and lactation has not been established.
  • Due to the Field Sorrel herb, consult your doctor if you are at risk of getting kidney stones, rheumatism, arthritis and gout.
  • This remedy should not be prescribed for patients who are sensitive to aspirin, or those taking anti-coagulant drugs such as warfarin. Primula Veris contains salicylates which are the main ingredient of aspirin.
  • Elder Flower taken together with diabetes medication might cause your blood pressure to be too low.
  • Not for use in children under 2 years of age.
  • Contains Sorbitol and may have a laxative effect. Patients with the rare hereditary condition of Sorbitol Intolerance, should not take Sinulex® Forte Syrup.
  • Stop using Sinulex® Forte Syrup at least 2 weeks before a scheduled surgery.
  • Protect from light, do not store above 25 °C and keep out of reach of children.
  • Do not use after the date of expiry.

Sinulex® Forte Syrup is available without a prescription from all leading pharmacies. Buy now

This medicine has not been evaluated by any regulatory body and is not intended to diagnose, treat, cure or prevent any disease.

See the package insert

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References

  1. J. Kim, J.Y. Um, S.H. Hong, and J.Y. Lee. Anti-inflammatory activity of hyperoside through the suppression of nuclear factor-κB activation in mouse peritoneal macrophages. American Journal of Chinese Medicine. Vol. 39, no. 1, pp. 171–181, 2011.
  2. EMA (European Medicines Agency). Assessment report on Primulaveris L. and/or Primulaelatior (L.) Hill, flos. EMA/HMPC/136583/2012, 2012.
  3. Zielińska-Pisklak and Ł. Szeleszczuk. Pierwiosnek, nie tylko zwiastun wiosny!, drug in Poland. Farmakoterapia. Vol. 23, no. 1, pp. 1–4, 2013.
  4. Gamze, A. Özmen, H. H. Biyik, and Ö. Şen. Antimitotic and antibacterial effects of the Primula veris L. flower extracts. Caryologia. Vol. 61, no. 1, pp. 88–91, 2008.
  5. D. Encyclopaedia of Herbs and their Uses.Dorling Kindersley, London. 1995 ISBN 0-7513-020-31
  6. S. & Duke. J. A. A Field Guide to Medicinal Plants. Eastern and Central N. America.Houghton Mifflin Co. 1990 ISBN 0395467225
  7. R. Encyclopaedia of Medicinal Plants.MacDonald 1984 ISBN 0-356-10541-
  8. A Modern Herbal. Penguin 1984 ISBN 0-14-046-440-9
  9. Sambucus nigra Elderberry – European Elder, Europea PFAF Plant Database. org.
  10. Healthcare journal of New Orleans. May / June 2017
  11. Deepak M, Handa SS. Antiinflammatory activity and chemical composition of extracts of Verbena officinalis. Phytother Res. 2000;14(6):463-465.
  12. Free for All. Thorsons Publishers 1977 ISBN 0-7225-0445-4
  13. J. The Herb Book.Bantam books 1983 ISBN 0-553-23827-2
  14. A. D. Herbs of Greece.Herb Society of America. 1970
  15. S. Y. The Dictionary of Modern Herbalism.
  16. Him-Che. Handbook of Chinese Herbs and Formulas.Institute of Chinese Medicine, Los Angeles 1985
  17. J. A. and Ayensu. E. S. Medicinal Plants of ChinaReference Publications, Inc. 1985 ISBN 0-917256-20-4
  18. D. Encyclopaedia of Herbs and their Uses.Dorling Kindersley, London. 1995 ISBN 0-7513-020-31
  19. Review of Natural Products. Facts & Comparisons [database online]. St. Louis, MO: Wolters Kluwer Health Inc; March 2011.
  20. Savikin K, Menkovic N, Zdunic G, Stevic T, Radanovic D, Jankovic T. Antimicrobial activity of Gentiana lutea L. extracts. Z Naturforsch C. 2009;64(5-6):339-342.19678535
  21. Calliste CA, Trouillas P, Allais DP, Simon A, Duroux JL. Free radical scavenging activities measured by electron spin resonance spectroscopy and B16 cell antiproliferative behaviors of seven plants. J Agric Food Chem. 2001;49(7):3321-3327.11453770

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